A Compilation of Our Research Contributions

Publications — 2026

1. Rawat K, Sandhu A, Kumar A, Saha L, Bhatia A, Saha PK, Walia R. Maternal choline and prebiotic supplementation ameliorate PCOS traits and reduce intergenerational transmission in rats. Life Sci. 2026;395:124385. DOI: 10.1016/j.lfs.2026.124385
2. Rawat K, Sandhu A, Kumar A, Saha L, Walia R, Saha PK, Bhatia A. BMI-dependent methylation and clinical signatures in North Indian women with PCOS. Indian J Med Res. 2026.
3. Zula P, Kakkar A, Saha L, Patil AN. Letter: Reconsidering tenofovir disoproxil fumarate use in light of emerging safety evidence. Aliment Pharmacol Ther. 2026;64(2):283–284. DOI: 10.1111/apt.70694
4. Haider A, Saha L, Basu D. Patterns of utilization of antipsychotic drugs and direct medical costs among patients with schizophrenia in a tertiary care hospital. World J Psychiatry. 2026;16(1):109365. DOI: 10.5498/wjp.v16.i1.109365

Publications — 2025

1. Uniyal M, Sandhu A, Gupta A, Rawat K, Kumar A, Singh S, et al. Dose optimization of NMDA for rat model of infantile spasms: approach using EEG, behavior (seizure) and histopathology. Behav Brain Res. 2025;495:115808. DOI: 10.1016/j.bbr.2025.115808

Publications (selected) — 2024

1. Saha L, Kumari P, Sinha VR, Gautam V, Kaur L, Sharma S, et al. Role of berberine nanoformulation in epilepsy: a novel therapeutic strategy. Epilepsy Res. 2024;205:107419. DOI: 10.1016/j.eplepsyres.2024.107419
2. Sandhu A, Rawat K, Gautam V, Kumar A, Sharma A, Bhatia A, et al. Neuroprotective effect of PPAR gamma agonist in rat model of autism spectrum disorder: role of Wnt/β-catenin pathway. Prog Neuropsychopharmacol Biol Psychiatry. 2024;135:111126.
3. Gautam V, Rawat K, Sandhu A, Medhi B, Bhatia A, Kharbanda PS, et al. Evaluation of Wnt/β-catenin signaling and its modulators in repeated dose lithium-pilocarpine rat model of status epilepticus: an acute phase study. Eur J Pharmacol. 2024;966:176375.
4. Sandhu A, Rawat K, Gautam V, Bhatia A, Grover S, Saini L, et al. Ameliorating effect of pioglitazone on prenatal valproic acid-induced behavioral and neurobiological abnormalities in autism spectrum disorder in rats. Pharmacol Biochem Behav. 2024;237:173721.
5. Sharma A, Kumar A, Rawat K, Vij S, Sandhu A, Gautam V, et al. Novel TMPRSS6 variants and their impact on iron-refractory iron deficiency anaemia in pregnancy: a North Indian genotype phenotype study. Br J Haematol. 2024;205(2):686–698. DOI: 10.1111/bjh.19616
6. Sharma A, Kumar A, Saha PK, Saha L. The role of TMPRSS6 gene polymorphism in iron resistance iron deficiency anaemia (IRIDA): a systematic review. Ann Hematol. 2024;103(4):1085–1102.
7. Kumar A, Ahmed B, Kaur IP, Saha L. Exploring dose and downregulation dynamics in lipid nanoparticles based siRNA therapy: systematic review and meta-analysis. Int J Biol Macromol. 2024;277(Pt 1):133984.
8. Kumar A, Saha L. Colorectal cancer cell dormancy: an insight into pathways. World J Gastroenterol. 2024;30(33):3810–3817.

• Publications — 2023
  1. Differential Regulation of Wnt/β-catenin Signaling in Acute and Chronic Epilepsy in Repeated Low Dose Lithium-Pilocarpine Rat Model of Status Epilepticus
  Rawat K, Gautam V, Sandhu A, Bhatia A, Saha L.
  Neuroscience. 2023;535:36–49.
  DOI: 10.1016/j.neuroscience.2023.10.019
  PMID: 37913863.
  Research area: Epilepsy • Wnt/β-catenin signaling • Neuropharmacology • Experimental pharmacology
  
  2. Neuroprotective effect of Berberine Nanoparticles Against Seizures in Pentylenetetrazole Induced Kindling Model of Epileptogenesis: Role of Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms
  Saha L, Kumari P, Rawat K, Gautam V, Sandhu A, Singh N, Bhatia A, Bhattacharya S, Sinha VR, Chakrabarti A.
  Neurochemical Research. 2023;48(10):3055–3072.
  DOI: 10.1007/s11064-023-03967-z
  PMID: 37329447.
  Research area: Epilepsy • Neuroprotection • Berberine nanoparticles • Oxidative stress • Neuroinflammation
  
  3. Phosphodiesterase inhibitor, ibudilast alleviates core behavioral and biochemical deficits in the prenatal valproic acid exposure model of autism spectrum disorder
  Sandhu A, Rawat K, Gautam V, Sharma A, Kumar A, Saha L.
  Brain Research. 2023;1815:148443.
  DOI: 10.1016/j.brainres.2023.148443
  PMID: 37290608.
  Research area: Autism spectrum disorder • Neuropharmacology • Ibudilast • Experimental therapeutics
  
  4. Modernising autism spectrum disorder model engineering and treatment via CRISPR-Cas9: A gene reprogramming approach
  Sandhu A, Kumar A, Rawat K, Gautam V, Sharma A, Saha L.
  World Journal of Clinical Cases. 2023;11(14):3114–3127.
  DOI: 10.12998/wjcc.v11.i14.3114
  PMID: 37274051.
  Research area: Autism • CRISPR-Cas9 • Gene editing • Disease modelling
  
  5. Current and emerging therapeutic approaches for colorectal cancer: A comprehensive review
  Kumar A, Gautam V, Sandhu A, Rawat K, Sharma A, Saha L.
  World Journal of Gastrointestinal Surgery. 2023;15(4):495–519.
  DOI: 10.4240/wjgs.v15.i4.495
  PMID: 37206081.
  Research area: Gastrointestinal oncology • Colorectal cancer • Therapeutics
  
  6. Generic ibrutinib a potential cost-effective strategy for the first-line treatment of chronic lymphocytic leukaemia
  Hegde NC, Kumar A, Kaundal S, Saha L, Malhotra P, Prinja S, Lad D, Patil AN.
  Annals of Hematology. 2023;102(11):3125–3132.
  DOI: 10.1007/s00277-023-05342-y
  PMID: 37439892.
  Research area: Pharmacoeconomics • Hematology • Drug utilization • Cost-effectiveness
  
  Publications — 2022
  1. Liver injury induced by COVID-19 treatment – what do we know?
  Saha L, Vij S, Rawat K.
  World Journal of Gastroenterology. 2022;28(45):6314–6327.
  DOI: 10.3748/wjg.v28.i45.6314
  PMID: 36533104.
  Research area: COVID-19 • Drug-induced liver injury • Clinical pharmacology • Drug safety
  
  2. Role of genomic DNA methylation in PCOS pathogenesis: a systematic review and meta-analysis involving case-controlled clinical studies
  Rawat K, Sandhu A, Gautam V, Saha PK, Saha L.
  Molecular Human Reproduction. 2022;28(8):gaac024.
  DOI: 10.1093/molehr/gaac024
  PMID: 35789386.
  Research area: PCOS • Epigenetics • DNA methylation • Reproductive pharmacology
  
  3. Relative refractoriness of breast cancer cells to tumour necrosis factor-α induced necroptosis
  Thakur B, Saha L, Bhatia A.
  Clinical and Experimental Pharmacology & Physiology. 2022;49(12):1294–1306.
  DOI: 10.1111/1440-1681.13711
  PMID: 36054417.
  Research area: Cancer pharmacology • Necroptosis • Breast cancer • Molecular pharmacology
  
  Publications — 2021
  1. An insight into crosstalk among multiple signaling pathways contributing to epileptogenesis
  Gautam V, Rawat K, Sandhu A, Kumari P, Singh N, Saha L.
  European Journal of Pharmacology. 2021;910:174469.
  DOI: 10.1016/j.ejphar.2021.174469
  PMID: 34478688.
  Research area: Epileptogenesis • Signaling pathways • Neuropharmacology
  
  2. A randomized controlled trial comparing the efficacy, tolerability, and cost of oral iron preparations in iron-deficiency anemia in pregnancy
  Gamad N, Saha PK, Sharma P, Suri V, Chakrabarti A, Saha L.
  Journal of Obstetrics and Gynaecology Research. 2021;47(11):3828–3841.
  DOI: 10.1111/jog.14999
  PMID: 34490696.
  Research area: Clinical pharmacology • Pharmacoeconomics • Iron-deficiency anemia • Pregnancy
  
  3. Identification of At-risk Pregnant Population for Over-the-Counter Drug Usage in Low-Resource Settings
  Arora A, Kumar MP, Anand A, Saha L, Saha PK, Kumar A, Shendge H, Patil AN.
  Journal of Obstetrics and Gynaecology of India. 2021;71(6):600–608.
  DOI: 10.1007/s13224-021-01481-2
  PMID: 34898898.
  Research area: Drug utilization • Pregnancy • Medication safety • Rational drug use
  
  4. Chlorhexidine-alcohol versus povidone-iodine as preoperative skin antisepsis for prevention of surgical site infection in cesarean delivery—a pilot randomized control trial
  Luwang AL, Saha PK, Rohilla M, Sikka P, Saha L, Gautam V.
  Trials. 2021;22(1):540.
  DOI: 10.1186/s13063-021-05490-4.
  Research area: Clinical pharmacology • Antiseptics • Obstetrics • Randomized controlled trials
  
  5. Iron nanoparticles and its potential application: A literature review
  Saha PK, Saha L.
  Indian Journal of Pharmacology. 2021;53(4):339–340.
  DOI: 10.4103/ijp.ijp_785_20
  PMID: 34414917.
  Research area: Nanomedicine • Iron metabolism • Drug delivery
  
  6. COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies
  Rawat K, Kumari P, Saha L.
  European Journal of Pharmacology. 2021;892:173751.
  DOI: 10.1016/j.ejphar.2020.173751
  PMID: 33245898.
  Research area: COVID-19 • Vaccines • Drug development • Clinical pharmacology
  
  Publications — 2020
  1. Pipeline Pharmacological Therapies in Clinical Trial for COVID-19 Pandemic: A Recent Update
  Kumari P, Rawat K, Saha L.
  Current Pharmacology Reports. 2020;6(5):228–240.
  DOI: 10.1007/s40495-020-00226-5
  PMID: 32837854.
  Research area: COVID-19 • Pharmacological treatment • Drug development • Clinical trials
  
  2. A review on preventive role of ketogenic diet (KD) in CNS disorders from the gut microbiota perspective
  Rawat K, Singh N, Kumari P, Saha L.
  Reviews in the Neurosciences. Published online 2020; subsequently indexed in 2021, 32(2):143–157.
  DOI: 10.1515/revneuro-2020-0078
  PMID: 33070123.
  Research area: Gut–brain axis • Gut microbiota • Ketogenic diet • Neurological disorders
  
  
  3. Aneurysmal Subarachnoid Hemorrhage: Impact on Phenytoin Permeability across the Blood-Brain Barrier
  Dhir N, Attri SV, Pattanaik S, Kumar MP, Gill NK, Patial A, Rathore N, Saha L, Mohindra S.
  Neurology India. 2020;68(3):588–592.
  DOI: 10.4103/0028-3886.288987
  PMID: 32643669.
  Research area: Clinical pharmacology • Neuropharmacology • Phenytoin • Blood–brain barrier
  
  4. Impact of COVID-19 on Medical Education in India: A Student’s Perspective
  Saha P, Saha L.
  Journal of Clinical and Diagnostic Research. 2020;14(11):IL01.
  DOI: 10.7860/JCDR/2020/45538.14185.
  Research area: Medical education • COVID-19 • Undergraduate medical education
  
  

Link for publications https://scholar.google.com/citations?hl=en&user=Om0CMhUAAAAJ&view_op=list_works&sortby=pubdate